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FAH Protein, Human, Recombinant (His)
Catalog Number: orb1961434
| Catalog Number | orb1961434 |
|---|---|
| Category | Small Molecules |
| Description | FAH Protein, Human, Recombinant (His) |
| Purity | 98.00% |
| MW | 43 KDa, reducing conditions |
| Biological Activity | Fumarylacetoacetase belongs to the FAH family. Fumarylacetoacetase is primary expressed in liver and kidney. It exists as a homodimer and catalyzes the hydrolysis of 4-fumarylacetoacetate into fumarate and acetoacetate. Defects in Fumarylacetoacetase cause tyrosinemia type 1, which is congenital metabolism defect characterized by elevated levels of tyrosine in the blood and urine, and hepatorenal manifestations. Typical features include renal tubular injury, self-mutilation, hepatic necrosis, episodic weakness, and seizures. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Recombinant Human Fumarylacetoacetase/FAH Protein, His Tag [orb1552362]
≥90% as determined by SDS-PAGE
This protein contains the human FAH(Ser2-Ser419) was fused with the C-terminal His Tag and expressed in Mammalian cells.
100 μg, 50 μg
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