EYA1/4 Antibody

• Catalog Number: orb1730033
• Category: Antibodies
• Description: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (By similarity). Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ELISA, IHC
• Reactivity: Human, Mouse
• Isotype: Rabbit IgG
• Immunogen: Synthetic peptide from human protein at AA range: 271-320
• Dilution range: IHC: 1/50-1/100; ELISA: 1/10000
• Conjugation: Unconjugated
• Entrez: 2070, 2138
• UniProt ID: O95677, Q99502
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: Eyes absent homolog 1; Eyes absent homolog 4
• Note: For research use only
• Expiration Date: 12 months from date of receipt.