Exatecan intermediate 9

SKU: orb2663880

Description

Exatecanintermediate 9 is an intermediate used in the synthesis of Exatecan. Exatecan (DX-8951) is a common toxin component in the preparation of Antibody-Drug Conjugates (ADC Cytotoxin) and also acts as an inhibitor of DNA topoisomerase I (topoisomerase I), with an inhibition concentration (IC50) of 2.2 μM.

Key Properties

• CAS Number: 2290562-59-1
• MW: 477.48
• Formula: C₂₆H₂₄FN₃O₅
• SMILES: N(C(C)=O)C1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6
• Target: ADC Cytotoxin

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

ADC Cytotoxin