Evofosfamide(TH-302)

• Catalog Number: orb198448
• Category: Small Molecules
• Description: TH-302 is selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM, demonstrates 270-fold enhanced cytotoxicity under hypoxia versus their potency under aerobic conditions, stable to cytochrome P450 metabolism.
• CAS Number: [918633-87-1]
• MW: 449.04
• SMILES: CN1C(=CN=C1[N+](=O)[O-])COP(=O)(NCCBr)NCCBr
• Formula: C₉H₁₆Br₂N₅O₄P
• Note: For research use only
• Expiration Date: 12 months from date of receipt.