ESR1 isoform1 antibody

• Catalog Number: orb107108
• Category: Antibodies
• Description: Rabbot polyclonal to ESR1 isoform1. This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Clone Number: RB41149
• Tested applications: IF, WB
• Predicted Reactivity: Equine, Mouse, Porcine, Rat
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: Synthetic Peptide
• Dilution range: WB: 1:1000, IF/ICC: 1:10-50
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• MW: 66216
• Target: ESR1
• UniProt ID: P03372
• NCBI: NP_001116214.1, NP_001116212.1, NP_000116.2, NP_001116213.1
• Alternative names: anti ESR1 antibody, anti ESR antibody, anti NR3A1
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Confocal immunofluoroscence analysis of MCF-7 cell using ESR1 isoform1 antibody(C-term)