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Endoglin/CD105 Protein, Human, Recombinant (His & Avi)
Catalog Number: orb1960530
| Catalog Number | orb1960530 |
|---|---|
| Category | Small Molecules |
| Description | Endoglin/CD105 Protein, Human, Recombinant (His & Avi) |
| Purity | 98.00% |
| MW | The protein has a predicted MW of 63.7 kDa. Due to glycosylation, the protein migrates to 70-82 kDa based on Tris-Bis PAGE result. |
| Biological Activity | Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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