EHMT2 antibody

• Catalog Number: orb67069
• Category: Antibodies
• Description: Rabbit polyclonal to EHMT2.Euchromatic histone-lysine N-methyltransferase 2 (EHMT2) belongs to the histone-lysinemethyltransferase family, Suvar3-9 subfamily. EHMT2 specifically mono-and dimethylates 'Lys-9' ofhistone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tagfor epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT2also weakly methylates 'Lys-27' of histone H3 (H3K27me). In addition, EHMT2 is required for DNAmethylation, which is independent of its histone methyltransferase activity. Furthermore, EHMT2methylates non-histone proteins, including p53/TP53, CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6,KLF12 and itself.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: middle region of human EHMT2
• Dilution range: WB:1:1000-1:5000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 132
• UniProt ID: Q96KQ7
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-EHMT2 antibody,anti-Histonelysine Nmethyltran
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Hela using EHMT2 antibody