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DSR-141562

SKU: orb1089425

Description

DSR-141562 is a novel, orally active, and selective brain-penetrant phosphodiesterase 1 (PDE1) inhibitor. DSR-141562 shows preferential selectivity for human PDE1B with an IC50 of 43.9 nM, and the IC50 values for human PDE1A and 1C are 97.6 and 431.8 nM, respectively. DSR-141562 can be used for the study of positive symptoms, negative symptoms and cognitive impairments associated with schizophrenia.

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Key Properties

CAS Number2007975-22-4
MW414.42
Purity>98%
FormulaC19H25F3N4O3
SMILESO=C1N(C)C(OC[C@H]2CC[C@H](C(F)(F)F)CC2)=NN3C1=CN=C3C4CCOCC4

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

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DSR-141562 (orb1089425)

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