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DSP-4 hydrochloride

SKU: orb1219705

Description

DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC). is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number40616-75-9
MW313.06
Purity>98% (HPLC)
FormulaC11H16BrCl2N
SMILESCl.CCN(CCCl)Cc1ccccc1Br
TargetOthers
SolubilityDMSO:125 mg/mL (399.28 mM; Need ultrasonic)

Bioactivity

In Vivo
Animal model: rats. Dosage: 50 mg/kg. Administration: intraperitoneal, single. Result: Not visualized large projection neurons and the fibers of the LC.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Neurotoxin DSP 4 (hydrochloride)

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    313.06

    C11H16BrCl2N

    5 mg, 10 mg, 50 mg, 100 mg, 200 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

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