Drebrin antibody

• Catalog Number: orb154400
• Category: Antibodies
• Description: Mouse monoclonal antibody to Drebrin which developmentally regulated brain proteins highly expressed in brain neurons. It might play some role in cell migration, extension of neuronal processes and plasticity of dendrites, respectively. Decreases in Drebrin levels in the brain are associated with Alzheimers disease and Down syndrome.
• Clonality: Monoclonal
• Clone Number: DBN-N-03
• Tested applications: CyTOF, FC, WB
• Reactivity: Human
• Isotype: Mouse IgG2b
• Immunogen: Bacterially expressed N-terminal fragment of recombinant human drebrin (aa 1-326)
• Concentration: 1 mg/ml
• Dilution range: Western blotting: Positive control: REH, Nalm-6, HEK293 cells. Flow cytometry: Recommended dilution: 1-4 µg/ml. Intracellular staining.
• Purity: Purified by protein-A affinity chromatography.
• Conjugation: Unconjugated
• Target: Drebrin
• Entrez: 1627
• UniProt ID: Q16643
• Storage: Store at 2-8°C. Do not freeze.
• Buffer/Preservatives: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
• Alternative names: Anti-DBN antibody, anti-D0S117E antibody
• Note: For research use only
• Application notes: Western blotting: Positive control: REH, Nalm-6, HEK293 cells. Flow cytometry: Recommended dilution: 1-4 µg/ml. Intracellular staining.
• Expiration Date: 12 months from date of receipt.

Mass cytometry of brain tumor cells with anti-drebrin (DBN-N-03) 152Sm. Gated on singlets.

Western blotting analysis of drebrin expression in REH, Ramos, and Nalm-6 cell lysate using mouse monoclonal antibody DBN-N-03.