DPP

• Catalog Number: orb2277817
• Category: Small Molecules
• Description: DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstrating antiproliferative activity. It activates caspase-3 and cleaved poly ADP-ribose polymerase, inducing apoptosis. Furthermore, DPP enhances the maturation and antigen presentation of dendritic cells and exhibits in vivo safety [1].
• CAS Number: 2668267-47-6
• Purity: 98.00%
• MW: 926.7
• SMILES: C(=C/C1=CC=C(OCC([O-][Pt+4]([O-]C(COC2=CC=C(/C=C/C3=CC(OC)=CC(OC)=C3)C=C2)=O)([Cl-])([Cl-])([NH3])[NH3])=O)C=C1)\C4=CC(OC)=CC(OC)=C4
• Formula: C₃₆H₄₀Cl₂N₂O₁₀Pt
• Biological Activity: DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstrating antiproliferative activity. It activates caspase-3 and cleaved poly ADP-ribose polymerase, inducing apoptosis. Furthermore, DPP enhances the maturation and antigen presentation of dendritic cells and exhibits in vivo safety [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.