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DOTMA

DOTMA

Catalog Number: orb1685342

DispatchUsually dispatched within 3-5 working days
$ 140.00
Catalog Numberorb1685342
CategorySmall Molecules
DescriptionDOTMA is a cationic lipid and can be used as a non-viral vector for gene therapy. It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro.
CAS Number104872-42-6
Purity> 95%
MW670.58
SMILES[Cl-].CCCCCCCC\C=C\CCCCCCCCOCC(C[N+](C)(C)C)OCCCCCCCC\C=C\CCCCCCCC
FormulaC42H84ClNO2
Biological ActivityDOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) is a tetra-methylated DOTA analogue. DOTMA is a cationic lipid and can be used as a non-viral vector for gene therapy. It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro. It exhibits effective in vitro and in vivo gene transfection. DOTMA induces a positive charge on the liposomes and thus promotes efficient liposome- cell membrane interaction.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • DOTMA [orb1473095]

    > 98%

    104162-48-3

    670.57486

    C42H84NO2+.CL-

    1 g