DMAT

SKU: orb1299862

Description

DMAT

Research Area

Metabolism Research, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 749234-11-5
• MW: 476.79
• Purity: 99.48% (May vary between batches)
• Formula: C₉H₇Br₄N₃
• SMILES: CN(C)c1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1
• Target: Casein Kinase
• Solubility: 10% DMSO+90% Corn Oil:2.5 mg/mL (5.24 mM);DMSO:50 mg/mL (104.87 mM)

Bioactivity

• Target IC50:
  Pim2:1.6 μM |Pim3:0.097 μM |β-glucuronidase:1.7 μM |CK2:0.13 μM (IC50, Human CK2) |DYRK2:0.35 μM |HIPK2:0.37 μM |DYRK1A:0.41 μM |Pim1:0.148 μM |PKD1:0.18 μM |CDK2:0.64 μM|HIPK3:0.59 μM
• In Vivo:
  DMAT blocks cell growth and induces cell death in cancer cells, both in culture and in mouse xenografts.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Casein Kinase, Casein kinase II Inhibitor, CaseinKinase, CK2, CK2 Inhibitor, DMAT, Inhibitor, inhibit

Compound Identifiers

PubChem CID

5326976