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DLin-MC3-DMA

Catalog Number: orb507413

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$ 240.00
Catalog Numberorb507413
CategorySmall Molecules
DescriptionD-Lin-MC3-DMA(MC3) is the most potent cationic lipid that has been synthesized for Lipid nanoparticles (LNPs) to deliver the siRNA.
CAS Number1224606-06-7
Purity> 98%
MW641.61
SMILESCCCCC/C=C\C/C=C\CCCCCCCCC(OC(=O)CCCN(C)C)CCCCCCCC/C=C\C/C=C\CCCCC
FormulaC43H79NO2
Hazard InformationNon-Toxic
StoragePure form: -20°C/3 years,4°C/2 years; In solvent: -20°C/1 month
Alternative names1224606-06-7, D-Lin-MC3-DMA, (6Z,9Z,28Z,31Z)-Hepta
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NoteFor research use only
Application notesD-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
Expiration Date12 months from date of receipt.

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Ye Zeng 1, Mariona Estapé Senti 2, M Clara I Labonia 3, Panagiota Papadopoulou 1, Maike A D Brans 3, Inge Dokter 3 4, Marcel H Fens 5, Alain van Mil 3 4, Joost P G Sluijter 3 4, Raymond M Schiffelers 2, Pieter Vader 2 3, Alexander Kros 1 Fusogenic Coiled-Coil Peptides Enhance Lipid Nanoparticle-Mediated mRNA Delivery upon Intramyocardial Administration ACS Nano, 17(23), 23466–23477 (2023)

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Human

Gangyin Zhao 1 2, Ye Zeng 3, Wanli Cheng 4, Sofia Karkampouna 4 5, Panagiota Papadopoulou 3, Bochuan Hu 3, Shuya Zang 3, Emma Wezenberg 3, Gabriel Forn-Cuní 1, Bruno Lopes-Bastos 1, Marianna Kruithof-de Julio 5, Alexander Kros 3, B Ewa Snaar-Jagalska 1 Peptide-Modified Lipid Nanoparticles Boost the Antitumor Efficacy of RNA Therapeutics ACS Nano, (2025)

DLin-MC3-DMA

Chemical structure of DLin-MC3-DMA

  • Dlin-MeOH [orb1983102]

    99.95%

    1169768-28-8

    528.94

    C37H68O

    500 mg, 25 mg, 100 mg, 2 mg, 5 mg, 50 mg, 10 mg, 1 ml x 10 mm (in DMSO)
  • 119-23 [orb2815799]

    2953044-98-7

    908.47

    C58H105N3O4

    50 mg, 10 mg
  • AA-T3A-C12 [orb1818882]

    [2938207-23-7]

    1059.72

    C65H126N4O6

    100 mg
  • 4A3-SCC-PH [orb2703758]

    1948.09

    C91H171N3O16S12

    100 mg, 25 mg, 50 mg