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Catalog Number | orb507413 |
---|---|
Category | Small Molecules |
Description | D-Lin-MC3-DMA(MC3) is the most potent cationic lipid that has been synthesized for Lipid nanoparticles (LNPs) to deliver the siRNA. |
CAS Number | 1224606-06-7 |
Purity | > 98% |
MW | 641.61 |
SMILES | CCCCC/C=C\C/C=C\CCCCCCCCC(OC(=O)CCCN(C)C)CCCCCCCC/C=C\C/C=C\CCCCC |
Formula | C43H79NO2 |
Hazard Information | Non-Toxic |
Storage | Pure form: -20°C/3 years,4°C/2 years; In solvent: -20°C/1 month |
Alternative names | 1224606-06-7, D-Lin-MC3-DMA, (6Z,9Z,28Z,31Z)-Hepta Read more... |
Note | For research use only |
Application notes | D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle. |
Expiration Date | 12 months from date of receipt. |
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Ye Zeng 1, Mariona Estapé Senti 2, M Clara I Labonia 3, Panagiota Papadopoulou 1, Maike A D Brans 3, Inge Dokter 3 4, Marcel H Fens 5, Alain van Mil 3 4, Joost P G Sluijter 3 4, Raymond M Schiffelers 2, Pieter Vader 2 3, Alexander Kros 1 Fusogenic Coiled-Coil Peptides Enhance Lipid Nanoparticle-Mediated mRNA Delivery upon Intramyocardial Administration ACS Nano, 17(23), 23466–23477 (2023)
Applications
Reactivity
Chemical structure of DLin-MC3-DMA
99.95% | |
1169768-28-8 | |
528.94 | |
C37H68O |