Disitamab vedotin Antibody

SKU: orb1691193

Description

Disitamab vedotin (RC-48) is a HER2-targeting antibody-drug conjugate (ADC) that delivers the cytotoxic agent MMAE. It demonstrates potent anti-tumor activity in vitro and in vivo against gastric cancer models with varying HER2 expression, inhibiting proliferation and downregulating HER2 protein levels.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• Target: EGFR,Antibody-Drug Conjugates (ADCs)
• Molecular Weight: Approximately 144.15 kDa
• Purity: 98.00% (May vary between batches)
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Concentration: 20.6 mg/mL
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EGFR, Disitamab vedotin, ADCs, AntibodyDrug Conjugates (ADCs), Antibody-Drug Conjugates (ADCs), Antibody-Drug Conjugates, AntibodyDrugConjugates, AntibodyDrugConjugates(ADCs), RC 48, RC48, RC-48

Quick Database Links

Gene Symbol

EGFR,Antibody-Drug Conjugates (ADCs)