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Catalog Number | orb1290219 |
---|---|
Category | Antibodies |
Description | Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions of human IgG1 heavy-chain and kappa light-chain |
Species/Host | Mouse |
Clonality | Monoclonal |
Tested applications | SDS-PAGE |
Reactivity | Human |
CAS Number | 1363687-32-4 |
Isotype | IgG1-kappa |
Purity | > 95% |
Conjugation | Unconjugated |
MW | 145000.0 Da |
Target | ganglioside GD2 |
Source | CHO cells |
Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4°C short term (1-2 weeks). Store at -20 °C 12 months. Store at -80°C long term |
Buffer/Preservatives | PBS buffer pH 7.5 |
Alternative names | 14.18, MAb-14.18, MOAB Ch14.18 Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
CAS Number: 1363687-32-4
Recombinant | |
Unconjugated |
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