DEFB1 Protein, Human, Recombinant (hFc)

• Catalog Number: orb1955556
• Category: Small Molecules
• Description: DEFB1 Protein, Human, Recombinant (hFc)
• Purity: 98.00%
• MW: 31.8 kDa (predicted)
• Biological Activity: The DEFB1 gene, encoding for the constitutively expressed human beta-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been reported as contributing to hBD1 production impairment, leading to a greater susceptibility to be infected by oral pathogens, also leading to periodontitis. To counteract host immunity, Cryptosporidium parvum has evolved multiple strategies to suppress host antimicrobial defense. One such strategy is to reduce the production of the antimicrobial peptide beta-defensin 1 (DEFB1) by host epithelial cells. Beta-Defensin-1, an antimicrobial peptide encoded by the DEFB1 gene, is known to play an important role in lung mucosal immunity.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.