Decitabine, Free Base

• Catalog Number: orb153611
• Category: Small Molecules
• Description: Decitabine is a cytosine nucleoside analog and inhibits further DNA methylation after incorporated into DNA. Decitabine has shown activity in some hematologic disorders including myelodysplastic syndromes (MDS), acute myelogenous leukemia (AML) and chronic myelogenous leukemia (CML). Treatment of patients with sickle cell disease (SSD) with subcutaneous decitabine increased fetal hemoglobin (HbF) levels and improved SSD pathophysiology such as red cell adhesion, endothelial damage, and coagulation pathway activity without cytotoxicity.
• CAS Number: 2353-33-5
• Note: For research use only
• Application notes: DCT
• Expiration Date: 12 months from date of receipt.

Chemical structure of Decitabine, Free Base

Decitabine, Free Base: Dezocitidine, 5-aza-CdR, 5-aza-dC, AzadC, Dacogen