dBRD9 dihydrochloride

• Catalog Number: orb1910481
• Category: Small Molecules
• Description: dBRD9 dihydrochloride is a potent and selective degrader (PROTAC) of BRD9 with IC50 of 56.6 nM in MOLM-13 cells.dBRD9 is composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide.dBRD9 does not degrade BRD4 or BRD7 at concentrations up to 5 uM.dBRD9 exhibits antiproliferative effects in human AML cell lines.
• CAS Number: [2341840-98-8]
• MW: 820.29
• SMILES: O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC(NCCOCCOCCNC(=O)CN(C)CC3C(=CC(C4=CN(C)C(=O)C5=CN=CC=C45)=CC=3OC)OC)=C12.Cl
• Formula: C₄₀H₄₆CLN₇O₁₀
• Note: For research use only
• Expiration Date: 12 months from date of receipt.