DAPK2 Antibody

• Catalog Number: orb1732070
• Category: Antibodies
• Description: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421).
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: IHC, WB
• Reactivity: Rat
• Isotype: Rabbit IgG
• Immunogen: A synthetic peptide of human DAPK2
• Concentration: 1mg/ml
• Dilution range: WB: 1/500-1/1000; IHC: 1/50-1/100
• Conjugation: Unconjugated
• MW: Calculated MW: 43 kDa; Observed MW: 43 kDa
• Entrez: 23604
• UniProt ID: Q9UIK4
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: DAPK2; Death-associated protein kinase 2; DAP kina
• Note: For research use only
• Expiration Date: 12 months from date of receipt.