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DAPAGLIFLOZIN
Catalog Number: orb180837
| Catalog Number | orb180837 |
|---|---|
| Category | Small Molecules |
| Description | Dapagliflozin, also known as BMS-512148, is a drug used to treat type 2 diabetes approved in 2012 by FDA. Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2) which are responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter mechanism causes blood glucose to be eliminated through the urine. In clinical trials, dapagliflozin lowered HbA1c by 0.6 versus placebo percentage points when added to metformin. |
| CAS Number | [461432-26-8] |
| MW | 408.87 |
| SMILES | O[C@H]1[C@H](C2=CC=C(Cl)C(CC3=CC=C(OCC)C=C3)=C2)O[C@H](CO)[C@@H](O)[C@@H]1O |
| Formula | C21H25ClO6 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Chemical structure of DAPAGLIFLOZIN
Dapagliflozin [orb1305553]
99.74%
461432-26-8
408.87
C21H25ClO6
5 mg, 10 mg, 50 mg, 100 mg, 25 mg, 200 mg, 1 ml x 10 mm (in DMSO)Dapagliflozin impurity [orb1709930]
98%
960404-86-8
424.87
C21H25ClO7
1 ml x 10 mm (in DMSO), 2 mg, 10 mg, 5 mgO-Desethyl Dapagliflozin [orb1685562]
98%
864070-37-1
380.82
C19H21ClO6
10 mg, 5 mg, 1 mg, 100 mg, 50 mg, 25 mg, 1 ml x 10 mm (in DMSO)
