Dabrafenib (GSK2118436)

• Catalog Number: orb154735
• Category: Small Molecules
• Description: Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively. Phase 3.
• CAS Number: [1195765-45-7]
• MW: 519.5624
• SMILES: S1C(C2C([H])=C([H])N=C(N([H])[H])N=2)=C(C2C([H])=C([H])C([H])=C(C=2F)N([H])S(C2C(=C([H])C([H])=C([H])C=2F)F)(=O)=O)N=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
• Formula: C₂₃H₂₀F₃N₅O₂S₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of Dabrafenib (GSK2118436)