D4476 (D-4476)

• Catalog Number: orb180888
• Category: Small Molecules
• Description: D4476, a cell-permeant inhibitor of CK1δ (IC90 < 10 uM), suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a, D4476 originally identified as inhibitors of activin receptor-like kinase ALK5.
• CAS Number: [301836-43-1]
• MW: 398.414
• SMILES: O1C([H])([H])C([H])([H])OC2C([H])=C([H])C(=C([H])C1=2)C1=C(C2=C([H])C([H])=C([H])C([H])=N2)N([H])C(C2C([H])=C([H])C(C(N([H])[H])=O)=C([H])C=2[H])=N1
• Formula: C₂₃H₁₈N₄O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of D4476 (D-4476)