Cystatin SN Protein, Human, Recombinant (His)

Catalog Number: orb1957595

Catalog Number	orb1957595
Category	Small Molecules
Description	Cystatin SN Protein, Human, Recombinant (His)
Purity	98.00%
MW	15.6 kDa (predicted)
Biological Activity	Cystatin-SN, also known as Cystain-SA-I, Cystatin-1, Salivary cystatin-SA-1 and CST1, is a secreted protein which belongs to thecystatin family. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. Cystatin-SN / CST1 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Cystatin-SN / CST1 is also expressed in saliva, tears, urine and seminal fluid. Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Human salivary cystatins include Cystatin-S, Cystatin-S1, Cystatin-S2, Cystatin- SA, Cystatin-SN, Cystatin-C and Cystatin-D. Cystatin-SN is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin-S, although both inhibit ficin equally well.
Note	For research use only
Expiration Date	12 months from date of receipt.

Purity:	> 97% by SDS-PAGE.
Source:	KMP1113, Recombinant Human Cystatin SN/CST1 Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (Trp21-Ser141) of human Cystatin SN/CST1 (Accession #NP_001889.2) fused with a 6×His Tag at the C-terminus.

Sizes Available: 100 μg, 50 μg

Purity:	≥90% as determined by SDS-PAGE
Source:	This protein contains the human CST1(Trp21-Ser141) was fused with the C-terminal His Tag and expressed in Mammalian cells.