CUL4A antibody

• Catalog Number: orb66954
• Category: Antibodies
• Description: Rabbit polyclonal to CUL4A.CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNAdamage-response proteins. CUL4A is a core component of multiple cullin-RING-based E3 ubiquitinproteinligase complexes which mediate the ubiquitination and subsequent proteasomal degradationof target proteins. As a scaffold protein, CUL4A may contribute to catalysis through positioning of thesubstrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complexis dependent on the neddylation of the cullin subunit. CUL4A may be involved in ubiquitination of JUN,P53, CDKN1B and HOXA9.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human, Mouse
• Immunogen: N-terminal region of human CUL4A
• Dilution range: WB:1:1000-1:5000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 88
• UniProt ID: Q13619
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-CUL4A antibody,anti-Cullin4A antibody
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Hela(Lane1) and mouse testis(Lane2) using CUL4A antibody