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CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)
Catalog Number: orb1961166
| Catalog Number | orb1961166 |
|---|---|
| Category | Proteins |
| Description | Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physiologic conditions. CTGF is pathologically viewed as a central mediator of tissue remodeling and fibrosis of various organs, including the lung, heart, liver, and kidney. |
| Tag | C-6xHis |
| Purity | 96.00% |
| MW | 33-45 KDa (reducing condition) |
| UniProt ID | Q5M8T4 |
| Protein Sequence | Gln27-Ala349 |
| Expression System | HEK293 Cells |
| Biological Origin | Human |
| Biological Activity | Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physiologic conditions. CTGF is pathologically viewed as a central mediator of tissue remodeling and fibrosis of various organs, including the lung, heart, liver, and kidney. |
| Expression Region | Gln27-Ala349 |
| Storage | -20°C |
| Note | For research use only |
| Application notes | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Expiration Date | 6 months from date of receipt. |
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Recombinant human CTGF / CCN2 protein, C-His-Avi (HEK293) [orb1516473]
> 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC
Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
100 μg CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated [orb1959919]
> 95% as determined by Bis-Tris PAGE
38.4 kDa (predicted). Due to glycosylation, the protein migrates to 43-53 kDa based on Tris-Bis PAGE result.
1 mg, 500 μg, 100 μg
