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    COX-2-IN-17

    COX-2-IN-17

    Catalog Number: orb1687896

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    Catalog Numberorb1687896
    CategorySmall Molecules
    DescriptionCOX-2-IN-17
    CAS Number2411390-10-6
    Purity98%
    MW414.89
    SMILESC([C@@H](C(OC)=O)N)C1=CN(C=2C1=CC=CC2)C=3N=C(N=C(Cl)N3)N4CCCCC4
    FormulaC20H23ClN6O2
    Biological ActivityCOX-2-IN-17 (compound 10) is a potent and BBB-penetrated COX-2 (cyclooxygenase-2) inhibitor, with an IC 50 of 0.02 μM. COX-2-IN-17 shows anti-inflammatory and analgesic activities. COX-2-IN-17 attenuates hyperalgesia in the neurogenic phase as well as the inflammatory phase [1].
    NoteFor research use only
    Expiration Date12 months from date of receipt.
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