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Catalog Number | orb1960231 |
---|---|
Category | Small Molecules |
Description | Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His) |
Purity | 98.00% |
MW | The protein has a predicted MW of 25.7 kDa. Due to glycosylation, the protein migrates to 26-30 kDa based on Tris-Bis PAGE result. |
Biological Activity | Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 25.7 kDa and the accession number is H9EXC1-1. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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