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Catalog Number | orb181026 |
---|---|
Category | Small Molecules |
Description | CNX-774 is a potent, selective, and orally available small molecule inhibitor of Btk (IC50< 1 nM) that forms a ligand-directed covalent bond with Cys-481, a non-conserved amino acid within the active site of the enzyme. |
CAS Number | [1202759-32-7] |
MW | 499.49638 |
SMILES | O=C(NC)C1=NC=CC(OC2=CC=C(NC3=NC=C(F)C(NC4=CC=CC(NC(C=C)=O)=C4)=N3)C=C2)=C1 |
Formula | C26H22N7O3F |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Chemical structure of CNX-774
99.10% | |
1202759-32-7 | |
499.5 | |
C26H22FN7O3 |
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