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CNTF Protein, Rat, Recombinant
Catalog Number: orb1957472
| Catalog Number | orb1957472 |
|---|---|
| Category | Small Molecules |
| Description | CNTF Protein, Rat, Recombinant |
| Purity | 98.00% |
| MW | Approxiamtely 22.9 kDa |
| Biological Activity | Ciliary neurotrophic factor (CNTF) is a member of the cytokine family. It is a polypeptide hormone that has functions in promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. Its actions appear to be restricted to the nervous system. Ciliary neurotrophic factor (CNTF) has biological effects through the activation of a multi-subunit receptor complex, consisting of an extracellular CNTF binding subunit (CNTFα) and two transmembrane signal transduction proteins: glycoprotein gp130 and LIF receptor. CNTF is considered as a potent survival factor of neurons and oligodendrocyteands may be relevant in reducing tissue destruction during inflammatory attacks. CNTF also is a survival factor for neurons of the peripheral sensory sympathetic and ciliary ganglia. It has been reported that CNTF could be an agent that has therapeutic potential and possibly induces differentiation of large multipolar ganglionic phenotype in a subset of progenitors. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
- Item 1 of 1
- Item 1 of 1
Murine CNTF protein [orb107698]
HPLC, SDS-PAGE
Unconjugated
> 95% by SDS-PAGE and HPLC analyses
22.4kDa
500 μg, 100 μg, 5 μg - Item 1 of 1
Rat CNTF protein [orb107699]
HPLC, SDS-PAGE
Unconjugated
> 95% by SDS-PAGE and HPLC analyses
22.7 kDa
500 μg, 100 μg, 5 μg Recombinant CNTF, Human(HEK 293-expressed) [orb1494653]
22~28 kDa, observed by reducing SDS-PAGE.
HEK 293
50 μg, 10 μgCNTF Protein [orb2023526]
Greater than 99.0% as determined by (a) Analysis by Gel Filtration. (b) Analysis by SDS-PAGE.
5 μg
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