CMKLR1 Antibody

• Catalog Number: orb1730149
• Category: Antibodies
• Description: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ELISA, ICC, IHC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: The antiserum was produced against synthesized peptide derived from human CMKLR1. AA range:221-270
• Dilution range: WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/50-1/200; ELISA: 1/10000
• Conjugation: Unconjugated
• MW: Calculated MW: 42 kDa; Observed MW: 42 kDa
• Entrez: 1240
• UniProt ID: Q99788
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: DEZ; RVER1; ChemR23; CHEMERINR
• Note: For research use only
• Expiration Date: 12 months from date of receipt.