CLEC4E Protein, Human, Recombinant (His)

Catalog Number: orb1960955

Catalog Number	orb1960955
Category	Small Molecules
Description	CLEC4E Protein, Human, Recombinant (His)
Purity	98.00%
MW	26 KDa, reducing conditions
Biological Activity	C-Type Lectin Domain Family 4 Member E (CLEC4E) is a 219 amino acid single-pass type II membrane protein that contains one C-type Lectin domain. It is expressed in monocytes, CLEC4E functions as a downstream target of C/EBP β and is thought to play a role in the inflammatory response, possibly via transcriptional control of C/EBP β. CLEC4E may play a role in the response to inflammatory stimuli in peritoneal macrophages and may be involved in immune surveillance processes under transcriptional control of CEBPB. Human CLEC4E shares 67% sequence identity with its mouse counterpart, suggesting a similar function between species. CLEC-4E exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to a natural killer gene complex region on human chromosome 12.
Note	For research use only
Expiration Date	12 months from date of receipt.

Purity:	≥90% as determined by SDS-PAGE
Source:	This protein contains the human CLEC4E(Arg41-Leu219) was fused with the C-terminal His Tag and expressed in Mammalian cells.