Clcn3 antibody

• Catalog Number: orb149956
• Category: Antibodies
• Description: Mouse monoclonal to Clcn3 (ATTO-594). Clcn3 mediates the exchange of chloride ions against protons, and functions as an antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. It may play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could also help neuronal cells to establish short-term memory..
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: S258-5
• Tested applications: ICC, IHC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: IgG1
• Immunogen: Synthetic peptide amino acids 98-115 (cytoplasmic N-terminus) of rat Clcn3
• Concentration: 1 mg/ml
• Dilution range: WB (1:1000), IHC (1:1000), ICC/IF (1:100)
• Conjugation: ATTO-594
• MW: 90kDa
• Target: ClCN3
• Entrez: 84360
• UniProt ID: P51792
• NCBI: NP_445815.2
• Storage: Conjugated antibodies should be stored at 4°C
• Buffer/Preservatives: PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
• Alternative names: CIC3 antibody, CLC3 antibody, CLCN 3 antibody, Chl
• Note: For research use only
• Application notes: 1 µg/ml of SMC-408 was sufficient for detection of Clcn3 in 20 µg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
• Expiration Date: 12 months from date of receipt.