CISD1 Protein, Human, Recombinant (His)

• Catalog Number: orb1956474
• Category: Small Molecules
• Description: CISD1 Protein, Human, Recombinant (His)
• Purity: 98.00%
• MW: 11.3 kDa (predicted)
• Biological Activity: Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson's disease (PD), the loss of mitoNEET (CISD1), an iron-sulfur containing protein that regulates mitochondrial bioenergetics, results in mitochondrial dysfunction and loss of striatal dopamine and tyrosine hydroxylase. CDGSH iron sulfur domain 1 (CISD1, also termed mitoNEET), an iron-containing outer mitochondrial membrane protein, negatively regulates ferroptotic cancer cell death. At the cellular level, CISD1 gene expression increased during human adipocyte differentiation in correlation with adipogenic genes.Thus it is a possible role of CISD1 in obesity-associated dysfunctional adipogenesis in human VAT.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.