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Ciluprevir

Ciluprevir

Catalog Number: orb1706040

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Catalog Numberorb1706040
CategorySmall Molecules
DescriptionCiluprevir
CAS Number300832-84-2
Purity98%
MW774.93
SMILESC(O)(=O)[C@]12[C@@](C1)(/C=C/CCCCC[C@H](NC(OC3CCCC3)=O)C(=O)N4[C@](C(=O)N2)(C[C@@H](OC=5C6=C(N=C(C5)C=7N=C(NC(C)C)SC7)C=C(OC)C=C6)C4)[H])[H]
FormulaC40H50N6O8S
Biological ActivityCiluprevir is an effective and selective HCV NS3 protease inhibitor with proven antiviral effect in humans. Ciluprevir may be an antiviral agent for individuals infected with non-genotype-1 HCV. In vitro sensitivity studies with Ciluprevir showed a decrease in affinity for proteases of genotypes 2 and 3 (Ki: 80 to 90 nM) compared to genotype 1 enzymes (Ki: 1.5 nM).
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • Ciluprevir (BILN 2061) [orb1183530]

    > 98%

    [300832-84-2]

    774.9

    C40H50N6O8S

    2 mg
  • Ciluprevir [orb1971839]

    300832-84-2

    774.9

    C40H50N6O8S

    10 mg
  • Ciluprevir [orb1971840]

    300832-84-2

    774.9

    C40H50N6O8S

    5 mg