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Catalog Number | orb1706040 |
---|---|
Category | Small Molecules |
Description | Ciluprevir |
CAS Number | 300832-84-2 |
Purity | 98% |
MW | 774.93 |
SMILES | C(O)(=O)[C@]12[C@@](C1)(/C=C/CCCCC[C@H](NC(OC3CCCC3)=O)C(=O)N4[C@](C(=O)N2)(C[C@@H](OC=5C6=C(N=C(C5)C=7N=C(NC(C)C)SC7)C=C(OC)C=C6)C4)[H])[H] |
Formula | C40H50N6O8S |
Biological Activity | Ciluprevir is an effective and selective HCV NS3 protease inhibitor with proven antiviral effect in humans. Ciluprevir may be an antiviral agent for individuals infected with non-genotype-1 HCV. In vitro sensitivity studies with Ciluprevir showed a decrease in affinity for proteases of genotypes 2 and 3 (Ki: 80 to 90 nM) compared to genotype 1 enzymes (Ki: 1.5 nM). |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |