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CHST11 Protein, Human, Recombinant (His)
Catalog Number: orb1955764
| Catalog Number | orb1955764 |
|---|---|
| Category | Proteins |
| Description | CHST11, also known as C4ST-1, belongs to the sulfotransferase 2 family. CHST11 localizes to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving CHST11 gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. |
| Tag | C-His |
| Purity | 98.00% |
| MW | 38.4 kDa (predicted); 43 kDa (reducing conditions) |
| UniProt ID | Q9NPF2 |
| Expression System | Baculovirus Insect Cells |
| Biological Origin | Human |
| Biological Activity | CHST11, also known as C4ST-1, belongs to the sulfotransferase 2 family. CHST11 localizes to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving CHST11 gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. |
| Expression Region | A DNA sequence encoding the human CHST11 (Q9NPF2-2) (Met36-Glu347) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Met 36 |
| Storage | -20°C |
| Note | For research use only |
| Application notes | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Expiration Date | 6 months from date of receipt. |
