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Catalog Number | orb1959015 |
---|---|
Category | Small Molecules |
Description | CHRNB3 Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | 25.7 kDa (predicted) |
Biological Activity | Cholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protective in Parkinson's disease (PD), possibly because of nicotine action on brain nicotinic-acetylcholine receptors. The beta3 nicotinic-acetylcholine receptor subunit (encoded by CHRNB3) is depleted in the striatum of PD patients and associated with nicotine dependence. CHRNB3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.7 kDa and the accession number is Q05901. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human CHRNB3(Ile25-Leu232) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
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