Tumor Proliferation and Metastasis Antibody Panel

SKU: orb1519154

Description

This panel integrates markers for cytotoxic T cells (CD3E, CD8 alpha, Granzyme B), tumor cells (Cytokeratin), proliferation (Ki-67), and melanoma/neural crest lineage (SOX10). It supports studies on tumor growth, immune-mediated cytotoxicity, and metastatic potential in solid tumors.

Images & Validation

• Tested Applications: IF, IHC
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Clonality: Recombinant
• Target: CD3E Granzyme B CD8 alpha Cytokeratin Ki-67 SOX10
• Conjugation: Unconjugated

Storage & Handling

• Storage: 2 - 8°C
• Form/Appearance: Liquid
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CD3-epsilon; TCRE; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell antigen receptor complex, epsilon subunit of T3; CD antigen CD3e; IMD18; CD3e molecule, epsilon (CD3-TCR complex); CD3e antigen, epsilon polypeptide (TiT3 complex); T3E; Leu2 T-lymphocyte antigen; T-lymphocyte differentiation antigen T8/Leu-2; T-cell surface glycoprotein CD8 alpha chain; T-cell antigen Leu2; T8 T-cell antigen; T cell co-receptor; OKT8 T-cell antigen; Leu2; CD8 antigen, alpha polypeptide (p32); CD8; CD antigen CD8a; p32; SECT; fragmentin 2; T-cell serine protease 1-3E; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); Granzyme-2; HLP; Lymphocyte protease; cytotoxic T-lymphocyte proteinase 2; human lymphocyte protein; CGL1; cytotoxic serine protease B; Fragmentin-2; C11; CCPI; CGL-1; CSPB; CSP-B; CTLA1; CTLA-1; CTSGL1; cathepsin G-like 1; K10; Keratin-10; keratin, type I cytoskeletal 10; CK10; keratin 10, type I; KPP; Cytokeratin-10; CK-10; BIE; BCIE; cytokeratin 10; EHK; EBS4; NFJ; Keratin-14; keratin, type I cytoskeletal 14; K14; EBS3; Cytokeratin-14; cytokeratin 14; CK-14; CK14; keratin 14, type I; keratin, type I cytoskeletal 15; Cytokeratin-15; type I cytoskeletal 15; keratin-15, beta; keratin-15, basic; Keratin-15; CK15; K15; cytokeratin 15; CK-15; K1CO; keratin 15, type I; Keratin-16; PC1; KRT16A; keratin, type I cytoskeletal 16; keratin 16, type I; K1CP; focal non-epidermolytic palmoplantar keratoderma; FNEPPK; Cytokeratin-16; cytokeratin 16; CK-16; CK16; K16; NEPPK; K19; keratin, type I, 40-kd; keratin, type I cytoskeletal 19; K1CS; Keratin-19; Cytokeratin-19; cytokeratin 19; CK-19; CK19; 40-kDa keratin intermediate filament; keratin 19, type I; PPP1R105; antigen identified by monoclonal antibody Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; proliferation marker protein Ki-67; MIB-1; MIB-; KIA; antigen Ki67; Antigen KI-67; transcription factor SOX-10; SRY-related HMG-box gene 10; WS4C; WS4; SRY (sex determining region Y)-box 10; PCWH; dominant megacolon, mouse, human homolog of; DOM; WS2E

Detection of human CD3E (cyan), CD8 alpha (red), cytokeratin (yellow), granzyme B (green), Ki-67 (orange) and SOX10 (magenta) in FFPE breast carcinoma by IHC-IF. Secondary: HRP-conjugated goat anti-rabbit IgG and HRP-conjugated goat anti-mouse IgG. Substrate: Opal™ 480, 520, 570, 620, 690 and 780. Counterstain: DAPI (blue).

Quick Database Links

Gene Symbol

CD3E Granzyme B CD8 alpha Cytokeratin Ki-67 SOX10

UniProt

P01732, P07766, P13645, P46013, P19012, P08727, P08779, P56693, P10144, P02533

RefSeq:P02533, P01732, P08779, P19012, P46013, P13645, P10144, P08727, P56693, P07766