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Catalog Number | orb1961354 |
---|---|
Category | Small Molecules |
Description | CDKN2C Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | 17 KDa, reducing conditions |
Biological Activity | Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in skeletal muscle, pancreas, and heart. CDKN2C inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB and prevent the activation of the CDK kinases. Studies have been shown the roles of CDKN2C gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human CDKN2C(Met1-Gln168) was fused with the N-terminal His Tag and expressed in E. coli. |
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