CD8 alpha Protein, Human, Recombinant (aa 22-182, His & Avi), Biotinylated

• Catalog Number: orb1960755
• Category: Proteins
• Description: CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.
• Tag: C-His-Avi
• Purity: 98.00%
• MW: 20.5 kDa (predicted). Due to glycosylation, the protein migrates to 30-38 kDa based on Tris-Bis PAGE result.
• UniProt ID: P01732
• Expression System: HEK293 Cells
• Biological Origin: Human
• Biological Activity: CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.
• Expression Region: Ser22-Asp182
• Storage: -20°C
• Note: For research use only
• Application notes: Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
• Expiration Date: 6 months from date of receipt.