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Catalog Number | orb1993488 |
---|---|
Category | Antibodies |
Description | CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis. |
Clonality | Monoclonal |
Clone Number | MEM-118 |
Tested applications | FC |
Reactivity | Human, Primate |
Isotype | Mouse IgM |
Immunogen | HPB-ALL human T cell line |
Conjugation | PE/Cy5 |
Target | CD55 |
Entrez | 1604 |
UniProt ID | P08174 |
Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
Buffer/Preservatives | Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide |
Alternative names | DAF, CROM, CHAPLE Read more... |
Note | For research use only |
Application notes | Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Expiration Date | 12 months from date of receipt. |
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