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CD45 Antibody (Leukocyte marker)

Catalog Number: orb699517

DispatchUsually dispatched within 5-10 working days
$ 410.00
Catalog Numberorb699517
CategoryAntibodies
DescriptionCD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
Species/HostRabbit
ClonalityRecombinant
Clone NumberPTPRC/3881R
Tested applicationsIHC-P
ReactivityHuman
IsotypeRabbit IgG
ImmunogenRecombinant full-length human protein was used as the immunogen for the recombinant CD45 antibody.
Antibody TypePrimary Antibody
Dilution rangeImmunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
PurityProtein A affinity chromatography
ConjugationUnconjugated
Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Hazard InformationThis recombinant CD45 antibody is available for research use only.
UniProt IDP08575
StorageStore the recombinant CD45 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Buffer/Preservatives0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide
NoteFor research use only
Application notesOptimal dilution of the recombinant CD45 antibody should be determined by the researcher.
Expiration Date12 months from date of receipt.
CD45 Antibody (Leukocyte marker)

IHC staining of FFPE human tonsil with recombinant CD45 antibody (clone PTPRC/3881R). HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

CD45 Antibody (Leukocyte marker)

SDS-PAGE analysis of purified, BSA-free recombinant CD45 antibody (clone PTPRC/3881R) as confirmation of integrity and purity.

  • CD45 (Intracellular) [orb1294366]

    FC,  IF,  IHC,  WB

    Human

    Rabbit

    Polyclonal

    Unconjugated

    25 μl, 100 μl
  • CD45 (Extracellular) [orb1294367]

    FC,  IF,  IHC,  WB

    Human, Mouse

    Rabbit

    Polyclonal

    Unconjugated

    25 μl, 100 μl
  • CD45 Rabbit Polyclonal Antibody [orb1179]

    FC

    Mouse, Rat

    Human

    Rabbit

    Polyclonal

    Unconjugated

    100 μl, 200 μl, 50 μl
  • CD45 Rabbit Polyclonal Antibody [orb312177]

    ICC,  IF,  IHC-Fr,  IHC-P,  WB

    Bovine

    Human

    Rabbit

    Polyclonal

    Unconjugated

    200 μl, 100 μl, 50 μl
  • CD45RA Antibody (Leukocyte marker) [orb248519]

    FACS,  IF,  IHC-P,  WB

    Human

    Mouse

    Monoclonal

    Unconjugated

    20 μg