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Catalog Number | orb1881234 |
---|---|
Category | Antibodies |
Description | CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy. |
Clonality | Monoclonal |
Clone Number | 15E3 |
Tested applications | FC |
Reactivity | Human |
Isotype | Mouse IgG1 kappa |
Immunogen | CD303 ectodomain fused with human IgG Fc domain |
Conjugation | PE |
Target | CD303 |
Entrez | 170482 |
UniProt ID | Q8WTT0 |
Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
Buffer/Preservatives | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Alternative names | BDCA2, CLEC4C, DLEC, HECL, CLECSF7, CLECSF11, PRO3 Read more... |
Note | For research use only |
Application notes | Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Expiration Date | 12 months from date of receipt. |
Flow cytometry multicolor surface staining pattern of human peripheral blood mononuclear cells using anti-human CD303 (15E3) PE antibody (10 μl reagent / 100 μl of peripheral whole blood) and anti-human CD123 (6H6) APC antibody (10 μl reagent per milion cells in 100 μl of cell suspension).
Separation of human CD123 positive CD303 positive plasmacytoid dendritic cells (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD303 (15E3) PE antibody (10 μl reagent / 100 μl of peripheral whole blood).
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD303 (15E3) PE antibody (10 μl reagent / 100 μl of peripheral whole blood).
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