CD274 Antibody (PE/Cy7)

• Catalog Number: orb1993580
• Category: Antibodies
• Description: CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins. It can act as both costimulatory and coinhibitory molecule for T cells. Interaction with its receptor CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection. Even pathogens (e.g. Schistosoma) may exploit CD274 to evade an immune response. Besides CD279, existence of other receptor(s) for CD274 is likely.
• Clonality: Monoclonal
• Clone Number: 29E.2A3
• Tested applications: FC
• Reactivity: Human, Primate
• Isotype: Mouse IgG2b kappa
• Immunogen: Full length human CD274
• Conjugation: PE/Cy7
• Target: CD274
• Entrez: 29126
• UniProt ID: Q9NZQ7
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Alternative names: B7H1, PDL1, PDCD1L1, PDCD1LG1, PDCD1 ligand 1, B7-
• Note: For research use only
• Application notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
• Expiration Date: 12 months from date of receipt.