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Catalog Number | orb1993579 |
---|---|
Category | Antibodies |
Description | CD273 / PD-L2 (programmed death ligand-1), also known as B7-DC, is a member of the B7 family of regulatory proteins. It costimulates the proliferation of T cells, and mediates IFN gamma production. Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses. When interacting with CD279, it can act as a coinhibitor of the T cell function. CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas. |
Clonality | Monoclonal |
Clone Number | 24F.10C12 |
Tested applications | FC |
Reactivity | Human |
Isotype | Mouse IgG2a kappa |
Immunogen | human CD273 cDNA |
Conjugation | PE/Cy7 |
Target | CD273 |
Entrez | 80380 |
UniProt ID | Q9BQ51 |
Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
Buffer/Preservatives | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Alternative names | PDCD1LG2, B7DC, Btdc, PDL2, PDCD1L2, bA574F11.2, B Read more... |
Note | For research use only |
Application notes | Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Expiration Date | 12 months from date of receipt. |
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