CD271 Antibody (PE/Cy7)

• Catalog Number: orb1993536
• Category: Antibodies
• Description: CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
• Clonality: Monoclonal
• Clone Number: NGFR5
• Tested applications: FC
• Reactivity: Feline, Ferret, Human, Primate, Rabbit
• Isotype: Mouse IgG1
• Immunogen: Purified CD271 protein isolated from human melanoma cell line A875
• Conjugation: PE/Cy7
• Target: CD271
• Entrez: 4804
• UniProt ID: P08138
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Alternative names: TNFRSF16, NGFR, p75NTR, p75NGFR
• Note: For research use only
• Application notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Extracellular and intracellular staining.
• Expiration Date: 12 months from date of receipt.