CD244 Antibody (APC)

• Catalog Number: orb1993795
• Category: Antibodies
• Description: CD244 is a 70 kDa type I transmembrane glycoprotein containing four ITSM domains in its cytoplasmic part, serving as docking sites for both activating and inhibitory signaling molecules. Its extracellular ligand is CD48. CD244 is involved in non-MHC restricted cytotoxic activity of NK cells and acts as a costimulatory ligand for both NK cells and T cells. Interaction of CD244 with CD48 on T cells leads to the activation of both, but interaction with CD48 on other cells (e.g. tumor cells) can lead to inhibition of NK cell functions.
• Clonality: Monoclonal
• Clone Number: 2-69
• Tested applications: FC
• Reactivity: Human
• Isotype: Mouse IgG2a kappa
• Immunogen: human NK cells
• Conjugation: APC
• Target: CD244
• Entrez: 51744
• UniProt ID: Q9BZW8
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Alternative names: SLAMF4, 2B4, NAIL, NMRK
• Note: For research use only
• Application notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
• Expiration Date: 12 months from date of receipt.