CD22 Antibody [hL22 (Epratuzumab)], Rabbit IgG - Research Grade Biosimilar

• Catalog Number: orb1671891
• Category: Antibodies
• Description: CD22 Antibody [hL22 (Epratuzumab)], Rabbit IgG - Research Grade Biosimilar
• Clonality: Recombinant
• Clone Number: hL22 (Epratuzumab)
• Tested applications: Blocking, FC, IP
• Reactivity: Human, Primate
• Isotype: IgG kappa
• Immunogen: This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5–10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010).
• Antibody Type: Primary Antibody
• Concentration: batch dependent
• Conjugation: Unconjugated
• Target: CD22
• UniProt ID: P20273
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: Leu14, B-cell receptor CD22, B-lymphocyte cell adh
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Flow-cytometry using anti-CD22 antibody Epratuzum28. Human lymphocytes were stained with an isotype control (3.0 - panel A) or the rmeric version of Eptratuzum2 - panel B) at a concentration of 1 ug/ml for 30 mins at RT. After washing- bound antibody was detected using a AF488 conjugated donkey anti-ribody and cells analysed on a FACSCanto flow-cytometer.

Flow-cytometry using anti-CD22 antibody Epratuzum28. Rhesus monkey lymphocytes were stained with an isotype control (3.0 - panel A) or the rmeric version of Epratuzum2 - panel B) at a concentration of 1 ug/ml for 30 mins at RT. After washing- bound antibody was detected using a AF488 conjugated donkey anti-ribody and cells analysed on a FACSCanto flow-cytometer.

Flow-cytometry using anti-CD22 antibody Epratuzum28. Cynomolgus monkey lymphocytes were stained with an isotype control (3.0 - panel A) or the rmeric version of Epratuzum2 - panel B at a concentration of 1 ug/ml for 30 mins at RT. After washing- bound antibody was detected using a AF488 conjugated donkey anti-ribody and cells analysed on a FACSCanto flow-cytometer.