CD123 Antibody (PE/Cy7)

• Catalog Number: orb1993519
• Category: Antibodies
• Description: CD123 is the alpha chain of interleukin 3 receptor (IL-3R alpha). This subunit heterodimerizes with the interleukin 3 receptor beta chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the beta subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.
• Clonality: Monoclonal
• Clone Number: 6H6
• Tested applications: FC
• Reactivity: Human
• Isotype: Mouse IgG1
• Immunogen: IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells
• Conjugation: PE/Cy7
• Target: CD123
• Entrez: 3563
• UniProt ID: P26951
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Alternative names: IL3RA, MGC34174, hIL-3Ra
• Note: For research use only
• Application notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
• Expiration Date: 12 months from date of receipt.