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CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated

CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated

Catalog Number: orb1961919

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$ 460.00
Catalog Numberorb1961919
CategoryProteins
DescriptionHuman IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.
TagC-6xHis-Avi
Purity98.00%
MW35-45 KDa (reducing condition)
UniProt IDP14784
Protein SequenceAla27-Asp239
Expression SystemHEK293 Cells
Biological OriginHuman
Biological ActivityHuman IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.
Expression RegionAla27-Asp239
Storage-20°C
NoteFor research use only
Application notesReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Expiration Date6 months from date of receipt.